Promethazine is metabolized via the liver to a range of compounds; the sulfoxides of promethazine and N-demethylpromethazine are the predominant metabolites showing up inside the urine.
Most MAO inhibitors must also not be taken for 2 months ahead of treatment method using this type of medication. Check with your doctor when to begin or halt taking this medication.
Prescription drug abuse is definitely the intentional non-therapeutic usage of a prescription drug, even once, for its satisfying psychological or physiological consequences.
Drink lots of fluids when you are applying this medication Except if not directed by your doctor. The fluid can help loosen the mucus as part of your lungs.
Maintain out with the arrive at of kids and pets. This medication could be abused. Retain it in a secure position to protect it from theft. Never share it with any one. It is only for you personally. Promoting or making a gift of this medication is risky and towards the law.
An increased risk of particular malformations with codeine publicity such as respiratory malformations, spina bifida and congenital heart defects have been described in a few reports.
This medication might cause you to far more sensitive towards the Solar. Restrict your time while in the Sunlight. Avoid tanning booths and sunlamps. Use sunscreen and wear protective garments when outdoors. Notify your health care provider without delay if you can get sunburned or have pores and skin blisters/redness.
Retail outlet at area temperature away from gentle and moisture. Tend not to store in the toilet. Tend not to freeze. Keep all prescription drugs faraway from little ones and Animals.
The next adverse reactions happen to be recognized all through clinical experiments, while in the literature, or all through publish-approval use of codeine and/or promethazine.
Promethazine has an elimination 50 percent-lifetime of ten-14 hours, with excretion of metabolites showing from the urine and feces. The sulfoxides of promethazine and N-demethylpromethazine are classified as the predominant metabolites showing up from the urine.
Promethazine is really a phenothiazine derivative which differs structurally within the antipsychotic phenothiazines through the existence of the branched aspect chain and no ring substitution.
Postmarketing scenarios of respiratory despair, such as fatalities are actually described with utilization of promethazine in pediatric people.
This medication can dry up and thicken mucus with your lungs, rendering it more challenging to breathe and apparent Promethazine codeine syrup your lungs. To help you avoid this effect, consume an abundance of fluids Except if otherwise directed by your medical professional.
Overdosage: If you believe you have got taken an excessive amount of of the medicine Get hold of a poison Command center or crisis area simultaneously.